The European Rare Kidney Disease Reference Network



Thematic Area: Lipids

The following guidance documents have been adopted based on standardized reviews and are followed in all ERKNet centers:


KDOQI Clinical Practice Guideline for Nutrition in Children with CKD: 2008 update
(statements regarding lipids).

 Am J Kidney Dis 2009 Suppl 2; 53: S1-S124

Core Recommendations:
  1. Lipid profiling (total cholesterol, LDL cholesterol, HDL cholesterol, triglycerides) is recommended on an annual basis  
  2. Treatment with statins or statin/ezetimibe combination is not routinely recommended  
Comments by evaluators:
  • No parent or patient representatives, renal nurses or Play Specialists or support workers involved
  • Rigorous guideline development process, but very little data in children, so largely opinion based recommendations
  • Excellent guideline with a great deal of detail, but application 'on the shop floor' may be difficult