Research Project

Project Title:

Determinants of immunosuppressive dose requirements in children after solid organ transplantation

Project Type:

Observational Study, Enrolment ongoing
Adjunct biobank: DNA

Disease group(s):

Pediatric kidney transplantation

Project Summary:

To determine the course and determinants of individual immunosuppressive dose requirements and their side effects in children during long-term follow up after solid organ transplantation.

Study design:
Prospective single-centre study (University Hospitals Leuven) at the department of pediatric solid organ transplantation collecting patient/laboratory/ pharmacokinetic data (obtained during routine clinical care) in combination with pharmacogenetic analysis of recipient and donor

Lead principal investigator(s):

Noel Knops, Leuven

Co-investigator(s):

Elena Levtchenko, Leuven

Project Period:

04/2013   -   12/2021

Sponsors:

Local resources

ClinicalTrials.gov:

NCT01767350

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